- 1 Michael Hill
- 2 What is Locked-in Syndrome?
- 3 Locked-in Syndrome Caused by Basilar Artery Stroke
- 4 Causes of a Basilar Artery Stroke
- 5 Symptoms of a Basilar Artery Stroke
- 6 How is a Basilar Artery Stroke Diagnosed?
- 7 Treatment of a Basilar Artery Stroke
- 8 Treatment for Locked In Syndrome
Latest posts by Michael Hill (see all)
- Do You Know How to React to the Most Common Signs of a Stroke? - April 10, 2017
- Why Your Local Hospital Might Not Have The Right Treatment for Your Stroke - April 9, 2017
- Women More Likely to Get Delayed Stroke Treatment In Hospital - February 26, 2017
What is Locked-in Syndrome?
In the Count of Monte Cristo, Alexander Dumas described a character with locked-in syndrome: “He was like a corpse with eyes.”
Locked-in syndrome is a devastating condition in which a person can think and is aware of his surroundings but is trapped inside of a useless body.
Locked-in syndrome is characterized by total paralysis of nearly all of the voluntary muscles in the body except the eyes. Total locked-in syndrome involves paralysis of the eyes, as well.
Patients with locked-in syndrome have no cognitive deficits, meaning they are just as aware of their circumstances and surroundings as they were before suffering locked-in syndrome.
In some situations, patients with locked-in syndrome can communicate through blinking, moving their eyes, or engaging in some other coded message with non-paralyzed portions of their body. In cases of total locked-in syndrome, there is no ability to communicate as the eyes are also paralyzed.
People with locked-in syndrome are also unable to produce voluntary sounds. Although the vocal cords are not damaged, people with locked-in syndrome lack coordination between their voice and breathing.
Locked-in Syndrome Caused by Basilar Artery Stroke
The basilar artery is one of the major arteries that supplies oxygen rich blood to the brain. The basilar artery lies at the front of the brainstem, which is at the base of the skull at the top of the spinal cord.
The basilar artery is formed by the connection of two vertebral arteries. Together, the basilar artery and vertebral arteries (known as the vertebrobasilar system) are the main supply of blood to the back of the brain, known as the brain stem.
The brainstem coordinates movement and balance and plays a primary role in sleeping, dreaming, digestion, swallowing, breathing, vision and heart rate.
If the basilar artery blocked (also called “occluded”) and the patient is not aggressively treated to remove the blockage immediately, the patient can go on to suffer locked-in syndrome or death.
Causes of a Basilar Artery Stroke
There are generally two types of strokes: (1) an ischemic stroke (where blood flow is restricted because of blockage) and (2) a hemorrhagic stroke (where blood vessels burst and there is too much blood in the brain).
Almost all strokes are ischemic strokes, meaning the brain is not getting enough blood because an artery is blocked. About 4% of all ischemic strokes are caused by blockages in the basilar artery. Basilar strokes are rare and the most feared of all strokes.
The most common cause of basilar artery strokes is hardening of the arteries. The second most likely cause is a blood clot. Each of these results in the basilar artery becoming blocked or occluded, which limits the amount of oxygen rich blood that can be delivered to the brain.
If the brain is deprived of oxygen, the brain tissue will begin to die. A common phrase used by neurologists is “time lost is brain lost.”
In some cases, a brainstem stroke may be the result of an injury to an artery as a result of sudden head or neck movement.
Similar to risk factors for other strokes, risk factors for a basilar artery stroke include the following:
- High blood pressure
- Elevated cholesterol levels
- Rupture of an arterial wall
- Connective tissue diseases
- Orthopedic condition of the neck
Men are more commonly affected by basilar artery strokes than women. Sufferers of basilar artery strokes tend to be over the age of 50.
Symptoms of a Basilar Artery Stroke
Strokes due to occlusion or bleeding of the basilar artery can cause a variety of symptoms which include paralysis, difficulty breathing, swallowing, double vision, coma, and even death.
Some of the common symptoms of a basilar artery stroke include the following:
- Balance difficulty
- Double vision or loss of vision
- Loss of coordination
- Swallowing difficulty
- Difficulty pronouncing words
- Weakness in one-half of the body
- Memory loss
How is a Basilar Artery Stroke Diagnosed?
A basilar artery stroke, like other strokes, is diagnosed by the patient’s history and symptoms along with imaging performed on the brain. The imaging can be a CT or MRI scan.
Any delays in diagnosing a stroke can lead to long-term complications and death.
Treatment of a Basilar Artery Stroke
A stroke is a medical emergency and needs to be treated immediately. Treatment of a basilar artery stroke is similar to that of any stroke. There are two main treatments for stroke thrombolysis (injection of medications to dissolve a clot) and thrombectomy (invasive techniques to remove a clot).
Treatment may include administration of intravenous tissue plasminogen activator (tPA) which is effective as long as the patient has receives it within 4.5 hours of the onset of symptoms. tPA is commonly called a “clot buster” medication because it acts to dissolve the clot.
There are also interventional approaches that are available to remove blood clots from the basilar and other arteries, including a mechanical thrombectomy. A stent retriever is fed through the groin and up the circulatory system to the location of the clot. The physician is able to visualize the procedure on a screen. The stent is pushed through the clot. A wire mesh is released that becomes entangled in the clot. A balloon is inflated stopping blood flow so pieces of clot are not released. The wire mesh and the blood clot caught in it are withdrawn from the artery and the vessel is cleared.
It is important that these steps are taken to prevent the patient from suffering locked-in syndrome if a basilar artery stroke is suspected.
Treatment for Locked In Syndrome
There is currently no cure for locked-in syndrome. The future may hold greater advances in neural interface technology to allow patients with locked-in syndrome to communicate. Because the portions of the brain that control speech are not damaged, the hope remains that an implant or other device can capture brain activity responsible for speech and translate that activity directly into speech. This thought-to-speech technology is based, in part, on advances in technology permitting brain signals to control prosthetic limbs of patients. For now, however, any such technology is years from becoming a reality.
Current treatment available consists of measures by rehabilitation providers including physical, occupational, recreational, and speech therapists, psychologists, physicians, nurses, care managers, and engineering and technology specialists.
The treatment team cares for the patient and educates family members and caregivers on how to perform life sustaining activities, including transferring from a bed to wheel chair, dressing, feeding, bathing, toileting, and cleaning the patient. Because locked-in syndrome is permanent, the patient will need life sustaining care for the remainder of his or her life.
Michael A. Hill is an accomplished trial lawyer focusing on representing individuals who have suffered life changing injuries due to stroke. Michael practices in state and federal courts around the country and has argued cases in front of numerous appellate courts, including the Ohio Supreme Court. Michael has recorded several seven figure verdicts and settlements. Michael is a regular speaker for lawyers concerning litigation and trial practice. Michael is a member of The National Trial Lawyers Top 40 under 40, Top 10 Nursing Homes Lawyers, Top 25 Medical Malpractice Lawyers, Super Lawyers: Rising Star, and Multi-Million Dollar Advocates Forum.
Michael is from Flint, Michigan and received his undergraduate degree from Oberlin College in Oberlin, Ohio, where he was introduced to his wife, Hilary. Michael received his law degree from Case Western Reserve University School of Law where he graduated Magna Cum Laude. Michael and Hilary live in Lakewood, Ohio.